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Accession number;03A0150476
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| Title;Incidence of glaucoma in patients of collagen disease and the implication of long-term systemic corticosteroid. |
| Author;
NAGAYAMA MIKIO
(Okamotodai Daigakuin'ishigakusogokenkyuka Ganka)
()
()
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Journal Title;Japanese Journal of Clinical Ophthalmology
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Journal Code:Z0515B
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ISSN:0370-5579
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VOL.57;NO.2;PAGE.119-123(2003)
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| Figure&Table&Reference;FIG.2, TBL.3, REF.11 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;We evaluated 244 patients of collagen disease regarding the presence of various types of glaucoma. Normal-tension glaucoma(NTG) was present in 4 cases(1.6%) and open-angle glaucoma in 3 cases(1.2%). Out of 172 cases receiving systemic corticosteroid for 1 year or longer, corticosteroid appeared to be the cause of raised intraocular pressure(IOP) in 6 cases(3.5%). The daily dosis of corticosteroid averaged 7.5.+-.2.25mg of prednisolone equivalent in the group of raised IOP and 7.5.+-.2.9mg in that of non-raised IOP. There was no significant difference between the two groups. The duration of corticosteroid treatment averaged 11.+-.9.9 years in the former and 11.+-.6.5 years in the latter. There was no significant difference between the two groups. Patients of Sjoegren disease had no NTG, while NTG was present in 3% of patients of chronic rheumatic arthritis and scleroderma. The findings show that the incidence of NTG is the same in patients of collagen disease and in the normal population. Patients under long-term corticosteroid have a low risk of raised IOP when the daily dosis is less than 10mg of prednisolone equivalent. (author abst.) |
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