Science Links Japan | Indications of Endoscopic Mucosal Resection (EMR) for Submucosal Invasive Gastric Cancer with Special Reference to Histopathologic Findings. Reserch by Using Logistic Regression Analysis Method.

Indications of Endoscopic Mucosal Resection (EMR) for Submucosal Invasive Gastric Cancer with Special Reference to Histopathologic Findings. Reserch by Using Logistic Regression Analysis Method.

Accession number;03A0197683

Title;Indications of Endoscopic Mucosal Resection (EMR) for Submucosal Invasive Gastric Cancer with Special Reference to Histopathologic Findings. Reserch by Using Logistic Regression Analysis Method.

Author; YASUDA MITSUGU (Kagawakengankenshinse Shokakika) NIKI MIYAKO (Kagawa-ken Gan Kenshin Senta) TORISU RYUSUKE (Kagawa-ken Gan Kenshin Senta) BANDO GENTARO (Kagawa-ken Gan Kenshin Senta) HAYASHI TOORU (Kagawa-ken Gan Kenshin Senta) SAKASHITA OSAMU (Kagawa-ken Gan Kenshin Senta) TAKAHASHI YOSHINORI (Kagawakengankenshinse Naika) YAMANOI AKIRA (Kagawa-ken Gan Kenshin Senta) YAMAMOTO YOSUKE (Kagawakengankenshinse Byori)

Journal Title;Gastroenterol Endosc

Journal Code:G0608B

ISSN:0387-1207

VOL.45;NO.3;PAGE.233-240(2003)

Figure&Table&Reference;FIG.1, TBL.8, REF.27

Pub. Country;Japan

Language;Japanese

Abstract;To clarify the risk factors for lymph node metastasis of submucosal invasive gastric cancer treated by endoscopic mucosal resection (EMR), we investigated the histopathologic findings of 194 surgically resected submucosal cancers. As for the histologic types, we reclassified these cancers according to the dominant histologic types within the mucosa. In the result, logistic regression analysis showed that the covariants which could predict lymph node metastasis were 1) papillary adenocarcinoma, 2) histologic heterogeneity in the submucosa, 3) lymphatic invasion. There were no lymph node metastasis and no abovementioned risk factors in lesions of differentiated submucosal cancers (tub1 or tub2) measuring 40mm or less in size with less than 500.MU.m invasion and measuring 20mm or less in size with less than 1000.MU.m invasion. Furthermore, tub1 or tub2 lesions with INF.ALPHA. showed lower lymph node metastasis significantly, suggesting that these risk factors would be useful for decision of EMR indication in borderline lesions. And we considered that to diagnose submucosal histological findings precisely, an enblock resection method should be performed. (author abst.)

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