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Accession number;03A0158568
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| Title;The mechanism of translation initiation in eukaryotes: Control by molecular mimics. |
| Author;
ASANO KATSURA
(Kanzasushudai)
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Journal Title;Protein, Nucleic Acid and Enzyme
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Journal Code:F0325A
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ISSN:0039-9450
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VOL.48;NO.4;PAGE.357-364(2003)
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| Figure&Table&Reference;FIG.4, REF.33 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Translation initiation in eucaryotes is a complicated reaction promoted at least by 11 translation initiation factors(eIF). Eucaryotic cells and viri infected to them control frequency of initiation of protein synthesis by changing a part of this reaction. Recent studies on both initiation and inhibition factors in molecular levels are revealing that translation control is accomplished by rearrangement of translation initiation mechanism by inhibition factor which partially mimicks initiation factor. This article describes this phenomenonon as "molecular mimicry", and trys to give a uniform review on the control mechanism of translation initiation. |
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