Diabetic Patient with "Takotsubo"-Like Cardiomyopathy Followed by Guillain-Barre Syndrome.
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Accession number;03A0177716
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| Title;Diabetic Patient with "Takotsubo"-Like Cardiomyopathy Followed by Guillain-Barre Syndrome. |
| Author;
TAKAMA HARUYUKI
(Seimariannaidai Taishanaibumpinaika)
NAGASAWA HISAKO
(Seimariannaidai Taishanaibumpinaika)
TOHYO SHUICHI
(Seimariannaidai Taishanaibumpinaika)
KATABAMI TAKUYUKI
(Seimariannaidai Taishanaibumpinaika)
SAITO NOBUHIKO
(Seimariannaidai Taishanaibumpinaika)
KONGOJI KEN
(St. Marianna Univ. School of Medicine, JPN)
AKASHI YOSHIHIRO
(St. Marianna Univ. School of Medicine, JPN)
HIRAYAMA TOSHIKAZU
(St. Marianna Univ. School of Medicine, JPN)
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Journal Title;Journal of the Japan Diabetic Society
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Journal Code:Z0279B
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ISSN:0021-437X
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VOL.46;NO.2;PAGE.117-123(2003)
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| Figure&Table&Reference;FIG.5, TBL.2, REF.18 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A 70-year-old woman hospitalized for muscular weakness in the extremities was found in electrocardio-graphy on admission to have ST-segment elevation in leads II, III, aVF and V1 through V4, and inverted T-waves were seen in II, III, aVF and V2 to V6. Although no stenotic lesion was detected in emergency coronary angiography, left ventriculography showed a hypokinetic area around the apex with an ejection fraction of 31%. 123I-MIBG myocardial scintigraphy showed an extensive defect around the apex. These findings supported a diagnosis of "Takotsubo"-like cardiomyopathy. Forty days after admission, albuminocytogenic dissociation of cerebrospinal fluid led us to diagnose Guillain-Barre syndrome as responsible for the weakness in the extremities. Guillain-Barre syndrome may damage the sympathetic nervous system, so we concluded that abnormality of the cardiac sympathetic nervous system due to Guillain-Barre syndrome and diabetic autonomic neuropathy caused cardiac dysfunction. Diabetes complicated "Takotsubo"-like cardiomyopathy followed by Guillain-Barre syndrome is extremely rare. (author abst.) |
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