Infiltrative Ability to the Matrix and Mechanical Effect of the Infiltration for Fibroblasts Derived from the Patellar Tendon-Comparisons between Extrinsic and Normal Fibroblasts.
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Accession number;03A0240718
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| Title;Infiltrative Ability to the Matrix and Mechanical Effect of the Infiltration for Fibroblasts Derived from the Patellar Tendon-Comparisons between Extrinsic and Normal Fibroblasts. |
| Author;
IKEMA YASUNARI
(Hokkaido Univ., Graduate School of Medicine, JPN)
TOOYAMA HARUKAZU
(Hokkaido Univ., Graduate School of Medicine, JPN)
NAKAMURA HIDEKI
(Hokudai Daigakuin'igakukenkyuka Chuokenkyubu)
KANAYA FUMINORI
(Univ. of Ryukyus, Fac. of Med.)
YASUDA KAZUNORI
(Hokkaido Univ., Graduate School of Medicine, JPN)
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Journal Title;Hokkaido Journal of Orthopedic and Traumatology
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Journal Code:Y0504A
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ISSN:1343-3873
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VOL.44;NO.2;PAGE.5-9(2003)
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| Figure&Table&Reference;FIG.6, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;To compare characteristics between the extrinsic fibroblasts(EF), which infiltrate into the necrotized patellar tendon(PT), and the normal PT fibroblasts(NF), the present in vitro experiment was performed. In 18 Japanese White rabbits, the right PT was necrotized with the in situ freeze-thaw technique. At 6 weeks after the treatment, bilateral PTs were resected and cultured to obtain the EFs and the NFs. Three PT matrix specimens after the freeze-thaw treatment were implanted into the 3 types of collagen gel clot, in which the cultured EFs, and no cells were seeded, respectively. The analysis using a confocal laser microscope showed that the number of infiltrated EFs into the matrix was significantly lower than that of the NFs at 1,3, and 6 weeks, On the other hand, the infiltration of the EFs or the NFs did not significantly affect the tangent modulus of the tendon matrix. (author abst.) |
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