The efficacy of epalrestat for muscle cramp in patients with lumbar spinal canal stenosis.

Accession number;03A0094004
Title;The efficacy of epalrestat for muscle cramp in patients with lumbar spinal canal stenosis.
Author; OGIWARA MASAHIRO (Naganosekijujibyoin Daiichimasuika) ASAKI CHIE (Naganosekijujibyoin Daiichimasuika) IWASAWA KEN (Naganosekijujibyoin Daiichimasuika) YONEZAWA KAORU (Naganosekijujibyoin Daiichimasuika) SAKAKI JUNTARO (Naganomatsushirosogobyoin Masuika) BABA KOSUKE (Nagano Prefect. Welf. Fed. of Agric. Coop. Hokushin Gen. Hosp.) KUMAKI SHOJI (Nagano Prefect. Welf. Fed. of Agric. Coop. Hokushin Gen. Hosp.)
Journal Title;Pain Clinic
Journal Code:G0739B
ISSN:0388-4171
VOL.24;NO.1;PAGE.76-80(2003)
Figure&Table&Reference;FIG.1, TBL.2, REF.12
Pub. Country;Japan
Language;Japanese
Abstract;Efficacy of daily oral treatment with epalrestat was investigated. Thirty patients with muscle cramp associated to lumbar spinal canal stenosis were given with epalrestat at 150 mg/day. For the group with no complication of diabetes, muscle cramp disappeared in 16 of 25 patients, whereas for the group complicated with diabetes, muscle cramp disappeared in 4 of 25. The symptoms were significantly improved in 84% of all subjects. However, neither of severe side effects not complication was found. Present results suggest that epalrestat is effective for either patient with or without complication of diabetes.