A girl with osteosarcoma who developed renal tubular acidosis due to ifosfamide.

Accession number;03A0187327
Title;A girl with osteosarcoma who developed renal tubular acidosis due to ifosfamide.
Author; NOGAMI AZUSA (Sapporo Medical Univ., School of Medicine, JPN) KUDO TOORU (Sapporo Medical Univ., School of Medicine, JPN) SUZUKI NOBUHIRO (Sapporo Medical Univ., School of Medicine, JPN) HORI TSUKASA (Sapporo Medical Univ., School of Medicine, JPN) HATAKEYAMA NAOKI (Sapporo Medical Univ., School of Medicine, JPN) MIZUE NOBUO (Sapporo Medical Univ., School of Medicine, JPN) TSUTSUMI HIROYUKI (Sapporo Medical Univ., School of Medicine, JPN)
Journal Title;Japanese Journal of Pediatric Oncology
Journal Code:X0797A
ISSN:0389-4525
VOL.39;NO.4;PAGE.538-541(2002)
Figure&Table&Reference;FIG.2, TBL.1, REF.12
Pub. Country;Japan
Language;Japanese
Abstract;Ifosfamide (IFO) is widely used for the infant solid tumor. A case presenting the renal tubular acidosis seemed to be caused by the IFO in about 1 year after the chemotherapy for osteosarcoma was reported. The case was a 10-year-old female infant, who was diagnosed as osteosarcoma of primary left thigh bone distance edge, and was hospitalized for the purpose of receiving the chemotherapy by the osteosarcoma Chemotherapeutic Inst. protocol. Though renal uriniferous tubule disorder at the end of the chemotherapy seemed to be reversible, it progressed in the latency afterwards and contracted the renal tubular acidosis after 1 year, and developed to the irreversible condition. The child patient has maintained the remission by the present, and the treatment for the renal uriniferous tubule failure becomes essential.