Two cases of metastatic tumors of the umbilicus (Sister Mary Joseph's nodule)
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Accession number;03A0557516
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| Title;Two cases of metastatic tumors of the umbilicus (Sister Mary Joseph's nodule) |
| Author;
MASAMUNE KATSUHIRO
(Tokushima Prefect. Kaifu Hosp.)
OTA KEN'ICHI
(Tokushima Prefect. Kaifu Hosp.)
FUJIKAWA KAZUYA
(Tokushima Prefect. Kaifu Hosp.)
HORIUCHI MASAFUMI
(Tokushima Prefect. Kaifu Hosp.)
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Journal Title;Shikoku Acta Medica
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Journal Code:G0586A
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ISSN:0037-3699
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VOL.59;NO.3;PAGE.153-158(2003)
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| Figure&Table&Reference;FIG.6, TBL.1, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The nodular umbilical metastasis of the visceral carcinoma has been termed the "Sister Mary Joseph's nodule" (SMJN), and is one of signs of a terminal condition. There are various routes of metastasis according to anatomical and embryological specificity. We report two cases of metastatic adenocarcinoma of the umbilicus, and also reviewed the 108 cases of SNJN that have been reported in Japan. The patients were 49 year-old man and 84 year-old woman who were referred to our hospital with umbilical nodules. Examination by computed tomographies, a biopsy and an extirpation of umbilical nodules showed that the primary malignancies were the pancreas cancer and the gallbladder cancer. Of 110 SMJN cases in Japan, thirty-one were men and seventy-six were women, and the primary focus was found in the stomach (45/103:39%), ovarium (18/103:13%), pancreas (14/103:15%) or colon (11/103:12%). In fifty-two cases (52/94:55%), initial presentation of the internal organ carcinoma was an umbilical nodule. It is generally reported that the prognosis of the patient with SMJN is extremely poor, but a few cases get the long survival after extirpation of SMJN. In order to decide proper treatment and prognosis, it is necessary us to further examine the primary malignancy and the route of metastasis for the SMJN patient. (author abst.) |
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