Longterm effect of once-daily dosing of zonisamide single agent for latency factor localization relevance epilepsy.

Accession number;03A0568610
Title;Longterm effect of once-daily dosing of zonisamide single agent for latency factor localization relevance epilepsy.
Author; MIURA TOSHIO (Kitasato Univ., Sch. of Med.) HOSODA NOZOMI (Kitasato Univ., Sch. of Med.)
Journal Title;Annual Report of the Research on Nervous and Mental Disorders 2002
Journal Code:N20031207
ISSN:
VOL.;NO.;PAGE.15(2003)
Figure&Table&Reference;REF.2
Pub. Country;Japan
Language;Japanese
Abstract;For infant of 72 examples of showing partial seizures which do not recognize clear psychomotor performance developmental disorder or neurological abnormality, once-daily dosing of zonisamide(ZNS) single agent was tried. Then, fluctuation of a blood concentration in the day and the clinical effect are exmined. In single agent treatment of ZNS, those which electroencephalogram is improved in early stage is also good in long term prognosis. However, when improvement of the electroencephalogram has been retarded, fit may reappear after it passes through over 5 years.