The Hemodynamic Effects of Acute Myocardial Ischemia and Reperfusion in Clawn Miniature Pigs.
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Accession number;03A0583411
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| Title;The Hemodynamic Effects of Acute Myocardial Ischemia and Reperfusion in Clawn Miniature Pigs. |
| Author;
KAMIMURA R
(Kagoshima Univ., Kagoshima, Jpn)
MIURA N
(Kagoshima Univ., Kagoshima, Jpn)
SUZUKI S
(Kagoshima Univ., Kagoshima, Jpn)
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Journal Title;Exp Anim
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Journal Code:Z0755A
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ISSN:1341-1357
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VOL.52;NO.4;PAGE.335-338(2003)
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| Figure&Table&Reference;FIG.1, TBL.1, REF.14 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Acute myocardial ischemia was induced by occluding the LAD in Clawn miniature pigs. Eight pigs(group 1) were subjected to 6h ischemia and nine pigs(group 2) were subjected to 20min ischemia, followed by reperfusion for 340min. Three animals of the group 1 died due to ventricular fibrillation after occlusion and in group 2, four animals died due to the arrhythmia after reperfusion. Though the ischemic area of group 2(15.6% of the ventricle) was narrower than that of group 1(21.7%), the survival rate was lower. We supposed that ischemia-reperfusion injuries were strongly connected with the hemodynamics of group 2. Clawn miniature pigs are useful experimental animals for myocardial ischemic researches. (author abst.) |
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