A New Method of Inhalation Anesthesia with Nasopharyngeal Insufflation in Rat Experiment.
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Accession number;03A0583414
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| Title;A New Method of Inhalation Anesthesia with Nasopharyngeal Insufflation in Rat Experiment. |
| Author;
YAMASAKI K
(Kagoshima Univ. Dental School, Kagoshima, Jpn)
KUROE K
(Kagoshima Univ. Dental School, Kagoshima, Jpn)
KAMIMURA R
(Kagoshima Univ., Kagoshima, Jpn)
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Journal Title;Exp Anim
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Journal Code:Z0755A
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ISSN:1341-1357
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VOL.52;NO.4;PAGE.349-351(2003)
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| Figure&Table&Reference;FIG.1, REF.8 |
| Pub. Country;Japan |
| Language;English |
| Abstract;We have established a new method of anesthesia with nasopharyngeal insufflation for intraoral procedure in rodents. Twelve male Wistar rats weighing 330-390g were used in this study. Insertion of a feeding tube 1.0mm in diameter coated with 2% xylocaine jelly was inserted into the nasal cavity approximately 25mm from the naris, and anesthetization with mixed gas of 100% oxygen with 3-4% enflurane at 0.25-0.5l/min flow rate was achieved. Using this anesthetic method, a chronic experiment comprising 1-h/day experimental procedure was carried out for 14 days. This method enabled, 1) simple and safe operation of the induction, emergence and anesthetic depth, 2) experimental procedures on the dental/oral region, 3) avoidance of the dyspnea and tachypnea, and 4) avoidance of cumulative effects in daily anesthesia. (author abst.) |
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