Validity and Application of Noninvasive Measurement of Blood Pressure in Hamsters.

Accession number;03A0583416
Title;Validity and Application of Noninvasive Measurement of Blood Pressure in Hamsters.
Author; KATO Y (Nagoya Univ., Nagoya, Jpn) IWASE M (Nagoya Univ., Nagoya, Jpn) NISHIZAWA T (Nagoya Univ., Nagoya, Jpn) ZHAO Y L (Sichuan Univ., Chengdu, Chn) TAKAGI K (Nagoya Univ., Nagoya, Jpn) NAGATA K (Nagoya Univ., Nagoya, Jpn) NODA A (Nagoya Univ., Nagoya, Jpn) KOIKE Y (Nagoya Univ., Nagoya, Jpn) YOKOTA M (Nagoya Univ., Nagoya, Jpn)
Journal Title;Exp Anim
Journal Code:Z0755A
ISSN:1341-1357
VOL.52;NO.4;PAGE.359-363(2003)
Figure&Table&Reference;FIG.3, TBL.2, REF.13
Pub. Country;Japan
Language;English
Abstract;The aim of this study was to examine both the validity and application of noninvasive measurement of blood pressure(BP) at the brachial artery in hamsters. There were significant correlations between noninvasive and invasive values for systolic BP(SBP), mean BP, and diastolic BP(r=0.96, r=0.93, r=0.88, respectively, all p<0.0001). Furthermore, SBP appeared to be the most accurate noninvasive BP index because both proportional and constant systematic errors were the least among the three indices. Peripheral vascular resistance calculated by combination with echocardiographic indices actually reflected the prominent .ALPHA.1-adrenergic drive induced by .BETA.-adrenergic blockers. In conclusion, noninvasive BP measurement at the brachial artery can provide useful information regarding the integrated cardiovascular function in hamsters. (author abst.)
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