Alpha 1-Acid Glycoprotein (AAG) Levels in Healthy and Pregrant Beagle Dogs

Accession number;03A0781107
Title;Alpha 1-Acid Glycoprotein (AAG) Levels in Healthy and Pregrant Beagle Dogs
Author; KURIBAYASHI T (Azabu Univ., Kanagawa) SHIMIZU M (Azabu Univ., Kanagawa) SHIMADA T (Azabu Univ., Kanagawa) HONJYO T (Azabu Univ., Kanagawa) YAMAMOTO Y (Farm Animal Clinic And Res. Center Inc., Tottori) KUBA K (Kitayama Labes Co., Ltd., Yamaguchi, Jpn) YAMAMOTO S (Azabu Univ., Kanagawa)
Journal Title;Exp Anim
Journal Code:Z0755A
ISSN:1341-1357
VOL.52;NO.5;PAGE.377-381(2003)
Figure&Table&Reference;FIG.1, TBL.1, REF.28
Pub. Country;Japan
Language;English
Abstract;Serum alpha 1-acid glycoprotein (AAG) levels were measured in healthy beagles of various ages (66 male and 74 female) by turbidimetric immunoassay (TIA), and then separately-in pregnant beagles-by single radial immunodiffusion (SRID). The first experiment revealed that serum AAG levels ranged from 40 to 960.MU.g/ml (mean of 322.+-.202.MU.g/ml) in male dogs, and from 47 to 833.MU.g/ml-in female dogs (mean of 316.+-.199.MU.g/ml), without any significant sex- or age-related variation. The second experiment, however, revealed that serum AAG levels increased in all pregnant beagles and peaked in the middle of gestation at 250-1,000.MU.g/ml (mean of 634.+-.246.MU.g/ml). In 7 of 8 dogs the AAG levels peaked about 45 days after ovulation. Despite a high value of 1,210-1,360.MU.g/ml being observed for serum AAG levels in 3 pregnant beagles inoculated with Staphylococcus aureus, its levels in umbilical cord blood were below the detection limit of SRID (40.MU.g/ml). (author abst.)
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