Multicentric Massive Osteolysis in the Trunk and Proximal Extremities: A Case Report
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Accession number;03A0705610
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| Title;Multicentric Massive Osteolysis in the Trunk and Proximal Extremities: A Case Report |
| Author;
TAKAHATA SHIGEO
(Sapporo Medical Univ., School of Medicine, JPN)
KAWAGUCHI SATOSHI
(Sapporo Medical Univ., School of Medicine, JPN)
NISHI MASAKO
(Sapporo Medical Univ., School of Medicine, JPN)
ISOGAI SATOSHI
(Sapporo Medical Univ., School of Medicine, JPN)
WADA TAKURO
(Sapporo Medical Univ., School of Medicine, JPN)
ISHII SEIICHI
(Sapporo Medical Univ., School of Medicine, JPN)
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Journal Title;Hokkaido Journal of Orthopedic and Traumatology
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Journal Code:Y0504A
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ISSN:1343-3873
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VOL.45;NO.1;PAGE.13-16(2003)
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| Figure&Table&Reference;FIG.4, TBL.1, REF.7 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Massive osteolysis is a rare condition in which spontaneous and progressive resorption of bone occurs. We report a case of the condition, which is categorized in the multicentric Gorham's massive osteolysis. Histological examination of the biopsy specimen revealed granulation tissue with distinct vascularization and reactive cell infiltration. The number of osteoclasts was not increased. The bone destruction was progressive and resisted against several treatments including rediotherapy, ultrasound therapy and administration of steroid, bisphosphonate and interferon .GAMMA.. The patient died of air-way obstruction due to increasing granulation tissue arising from the mandibula. (author abst.) |
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