A Case Report of the Man whose Skin Erosion caused by Food Debris that Leaked from a Tracheotomy Hole was Improved by Fudostein

Accession number;03A0865488
Title;A Case Report of the Man whose Skin Erosion caused by Food Debris that Leaked from a Tracheotomy Hole was Improved by Fudostein
Author; KATO SHIGEO (Shinfujibyoin Naika)
Journal Title;Journal of Clinical Therapeutics & Medicines
Journal Code:Y0906A
ISSN:0910-8211
VOL.19;NO.11;PAGE.1327-1330(2003)
Figure&Table&Reference;FIG.1, TBL.2, REF.3
Pub. Country;Japan
Language;Japanese
Abstract;A 59-year old man underwent tracheotomy because of dyspnea caused by cerebral infarct sequelae. Since oral feeding was impossible, he also underwent gastrostomy. During and after meals, viscous sputum mixed with food debris leaked from the hole of the tracheotomy site. The skin around the tracheotomy hole became sore, requiring treatment. When lansoprazole, one of the proton pump inhibitor, was given, food debris disappeared, but the viscosity of the sputum did not decrease; on the other hand, when expectorants such as bromhexine, ambroxol, and carbocysteine were given, sputum became seromucous, but food debris continued to be exuded. We treated the patient with Fudostein. About 4 days after beginning administration, the sputum level improved from purulent stage 2 (P2) to mucous stage 2 (M2) (Miller & Jones classification). Food debris leakage also decreased, followed by gradual improvement of the sore skin. No changes were observed in the volume of sputum. It is concluded that the above effectiveness results from the fact that Fudostein effectively suppresses the proliferation of respiratory embryonic cells under conditions of activation of the sympathetic nerve system seen during and after meals. (author abst.)