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Accession number;04A0127251
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| Title;Antibiotic Sensitivities of Mycobacterium avium Isolated from Pigs and the Diagnostic Significance of IFN-.GAMMA. Produced by Lymphocytes Stimulated with a Specific Antigen in Swine Mycobacteriosis |
| Author;
IWAKIRI AKIRA
(Miyazakikenmiyakonojoshokunikueiseikensasho)
GANNICHIDA SATOSHI
(Miyazakikenmiyakonojoshokunikueiseikensasho)
OGATA IKUO
(Miyazakikenmiyakonojoshokunikueiseikensasho)
YAMAMOTO SHIGEKI
(National Inst. Health Sciences, JPN)
GOTO YOSHITAKA
(Miyazaki Univ., Faculty of Agriculture, JPN)
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.57;NO.2;PAGE.117-120(2004)
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| Figure&Table&Reference;FIG.3, TBL.1, REF.11 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Multiplex PCR tests identified 69 strains of mycobacteria originated in pigs from 5 Japanese meat-inspection centers as Mycobacterium avium (M. avium). The sensitivities of 24 strains to 9 antibiotics were tested. All strains were shown to be 8 times more sensitive to streptomycin, rifampicin, clarithromycin, and amikacin than is indicated by previously reported data on M. avium strains originating in human beings [10]. Measurements of interferon-gamma (IFN-.GAMMA.) production by spleen cells or blood monocytes isolated from normal or infected pigs showed that IFN-.GAMMA. was produced in the swine-mycobacteriosis group if they were stimulated by the M. avium antigen in vitro. No production was observed in the healthy control group. This suggests that IFN-.GAMMA. assay is a valuable method for diagnosis of M. avium infection in swine. (author abst.) |
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