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STRATEGY IN MANAGEMENT OF T2 GLOTTIC SQUAMOUS CELL CARCINOMA

Accession number;04A0146731

Title;STRATEGY IN MANAGEMENT OF T2 GLOTTIC SQUAMOUS CELL CARCINOMA

Author; HANEDA TATSUMASA (National Cancer Center Hospital East, JPN) EBIHARA SATOSHI (National Cancer Center Hospital East, JPN) SAIKAWA MASAHISA (National Cancer Center Hospital East, JPN) HAYASHI RYUICHI (National Cancer Center Hospital East, JPN) ONITSUKA TETSURO (National Cancer Center Hospital East, JPN) KOMURO TETSU (National Cancer Center Hospital East, JPN) ASAKAGE TAKAHIRO (National Cancer Center Hospital East, JPN) OYAMA WAICHIRO (National Cancer Center Central Hospital, JPN) IKEDA HIROSHI (National Cancer Center Hospital East, JPN)

Journal Title;Head and Neck Cancer

Journal Code:Y0503A

ISSN:0911-4335

VOL.28;NO.1;PAGE.30-34(2002)

Figure&Table&Reference;FIG.1, TBL.2, REF.10

Pub. Country;Japan

Language;Japanese

Abstract;From 1980 through 1994, 71 patients with T2 glottic squamous cell carcinoma (SCC) were treated at National Cancer Center Hospital by radiotherapy, partial laryngectomy (PL), and total laryngectomy (TL). The results of the treatment in these patients were analyzed to determine a strategy for management of T2 glottic SCC. The 5-year, cause-specific survival rate in these patients was about 90%. The local control rates, and the laryngeal preservation rates, were 84% and 84% with PL, versus 47% and 58% with radiotherapy, but the voice quality after radiotherapy was clearly superior to that after PL. The laryngeal preservation rate in patients with T2 radiation-failure glottic carcinoma was just 21%, and TL was required in a majority of these patients. The diagnosis of subglottic extension in patients with T2 glottic SCC was very important to determine any type of treatment. TL should be initially required for patients with widespread subglottic extension. The decision on treatment should be selected by the patient himself after obtaining correct information about each treatment. (author abst.)

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