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Accession number;04A0146750
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| Title;POSTOPERATIVE EVALUATION OF THYROID PAPILLARY ADENOCARCINOMA WITH EXTRATHYROIDAL EXTENSION USING SERUM-THYROGLOBULIN |
| Author;
SHINOHARA SHOGO
(Kobe City General Hospital, JPN)
YAMAMOTO ETSUO
(Kobe City General Hospital, JPN)
TANABE MAKITO
(Kobe City General Hospital, JPN)
FUJIWARA KEIZO
(Kobe City General Hospital, JPN)
WATANABE FUTOSHI
(Kobe City General Hospital, JPN)
KIKUCHI MASAHIRO
(Kobe City General Hospital, JPN)
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Journal Title;Head and Neck Cancer
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Journal Code:Y0503A
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ISSN:0911-4335
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VOL.28;NO.1;PAGE.137-142(2002)
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| Figure&Table&Reference;FIG.3, TBL.2, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Most patients with thyroid papillary adenocarcinomas (PACs) have good prognosis but some show postoperative local recurrence or distant metastasis. Extrathyroidal extension (ETE) is known as a risk factor of distant metastasis. The postoperative serum-thyroglobulin (Tg) of the patients had PAC with ETE histologically (pT4 cases) between May 1987 and December 2000 was retrospectively examined. The subjects consisted of 43 patients, 1 patient was treated with palliative operations and 42 patients underwent curative operations (36 total thyroidectomies and 6 other operations). Simultaneous neck dissections (central compartment or more) were also performed in 40 cases. A metastatic lesion in cerebellum was removed in 1 case. Recurrent nerves were resected in 29 cases, tracheal cartilage in 19 cases, muscle layers of the esophagus or the sphinctor in 16 cases and the other organs in 7 cases. Postoperative radioiodine therapies were performed in 18 cases. The five-year and ten-year cause-specific survival rates with Kaplan-Meier method were both 97.1%. However, the postoperative serum-thyroglobulin were detected in 17 cases among 35 cases with curative total thyroidectomy. It was concluded that thyroid tissue remained somewhere in about 50% of pT4 cases even when curative total thyroidectomy was performed. (author abst.) |
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