PROGNOSTIC FACTORS AND A NOVEL RISK GROUP CLASSIFICATION OF PAPILLARY THYROID CARCINOMA
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Accession number;04A0146751
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| Title;PROGNOSTIC FACTORS AND A NOVEL RISK GROUP CLASSIFICATION OF PAPILLARY THYROID CARCINOMA |
| Author;
SUGITANI IWAO
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
YOSHIMOTO SEIICHI
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
MITANI HIROKI
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
HOKI KATSUFUMI
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
NIGAURI TOMOHIKO
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
KAWABATA KAZUYOSHI
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
KAMATA SHIN'ETSU
(Japanese Foundation for Cancer Res., Cancer Inst. Hospital, JPN)
YANAGISAWA AKIO
(Ganken Byoribu)
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Journal Title;Head and Neck Cancer
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Journal Code:Y0503A
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ISSN:0911-4335
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VOL.28;NO.1;PAGE.143-147(2002)
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| Figure&Table&Reference;FIG.1, TBL.2, REF.14 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Several factors have been proved useful to differentiate patients with papillary thyroid carcinoma into either a low-or high-risk group for cancer death. A referral cancer center like ours treats many advanced cases, where more sophisticated discrimination methods are required. Data were obtained from 604 patients who underwent initial surgery for papillary thyroid carcinoma (T>1cm) during the period from 1976 to 1998. The mean follow-up period was 10.7 years. In all, 32 patients died of the disease. The disease-specific 10-year survival rate was 94.0%. By multivariate analysis, distant metastasis, extrathyroidal invasion, and large nodal metastasis (.GEQ.3cm), in older patients (age.GEQ.50), and distant metastasis in younger patients (age<50), were significant risk factors. From the results, we defined older patients with any of the three factors, and younger patients with distant metastasis, as the high-risk group, and others as the low-risk group. A total of 498 low-risk patients (82.5%), and 106 high-risk patients (18.5%), had 10-year survival rates of 99.3% and 68.9%, respectively. The original risk group definition was useful to predict the prognosis of our patients with papillary thyroid carcinoma. (author abst.) |
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