HYPERFRACTIONATED RADIATION THERAPY FOR HYPOPHARYNGEAL CARCINOMA-PRELIMINARY RESULTS-

Accession number;04A0146755
Title;HYPERFRACTIONATED RADIATION THERAPY FOR HYPOPHARYNGEAL CARCINOMA-PRELIMINARY RESULTS-
Author; NIIBE YUZURU (Tokyo Metrop. Komagome Hospital, JPN) KARASAWA KATSUYUKI (Tokyo Metrop. Komagome Hospital, JPN) KAIZU TOSHIHIDE (Tokyo Metrop. Komagome Hospital, JPN) MIYASHITA HISAO (Tokyo Metrop. Komagome Hosp.) NAKAMURA YUZURU (Tokyo Metrop. Komagome Hosp.) SUZUKI MASAHIKO (Tokyo Metrop. Komagome Hosp.) UZAWA MASAMICHI (Tokyo Metrop. Komagome Hosp.) TANAKA YOSHIAKI (Nihon Univ., Sch. of Med.)
Journal Title;Head and Neck Cancer
Journal Code:Y0503A
ISSN:0911-4335
VOL.28;NO.1;PAGE.165-169(2002)
Figure&Table&Reference;FIG.2, TBL.5, REF.19
Pub. Country;Japan
Language;Japanese
Abstract;Sixteen patients with hypopharyngeal carcinoma treated with hyperfractionated radiation therapy from 1996 to 2000 were analyzed. The mean age was 65 years (range: 52-84yrs). The number of patients of Stage I, II, III and IV were 2, 5, 3 and 6, respectively. All patients were treated with 4MV X-ray using a shrinking field technique (initial field covered whole pharynx and neck). Fractionation was 1.2Gy/fraction, 2 fractions/day, 10 fractions/week and the mean total dose was 72Gy (range; 66-79.2Gy). Radiation response of hypopharygeal lesion at the end of treatment was as follows: CR: 13 (81.3%), PR: 3 (18.7%). 2-yrs overall survival and local control rates were 69.9%, 63.6%, respectively. In conclusion, the preminilary results of this study were relatively better than those of previous reports, which indicates that hyperfractionated radiaton therapy might be a promising treatment method for hypopharyngeal carcinoma. (author abst.)