CHANGE OF SONOGRAPHIC FINDINGS ON CERVICAL LYMPH NODES BEFORE AND AFTER PREOPERATIVE RADIOTHERAPY

Accession number;04A0146762
Title;CHANGE OF SONOGRAPHIC FINDINGS ON CERVICAL LYMPH NODES BEFORE AND AFTER PREOPERATIVE RADIOTHERAPY
Author; CHIKUI TOORU (Kyushu Univ., Graduate School of Dentistry, JPN) YUASA KENJI (Kyushu Univ., Facylty of Dentistry, Hospital, JPN) KANDA SHIGENOBU (Kyushu Univ., Graduate School of Dentistry, JPN) NAKAMURA KATSUMASA (Kyusyu Univ., School of Medical Sci., JPN) NAGATA TETSUJI (Kyushu Univ., Facylty of Dentistry, Hospital, JPN) HIRAKI AKIMITSU (Kyushu Univ., Facylty of Dentistry, Hospital, JPN)
Journal Title;Head and Neck Cancer
Journal Code:Y0503A
ISSN:0911-4335
VOL.28;NO.1;PAGE.211-217(2002)
Figure&Table&Reference;FIG.4, TBL.3, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;Objective To understand the changes in the sonographic findings of the lymph nodes before preoperative radiotherapy and after preoperative radiotherapy. In addition, we also evaluated the contribution of irradiation for prediction cervical lymph node metastasis. Materials and Methods We performed US examinations on 166 cervical lymph nodes (64 metastatic and 102 reactive nodes) before and after radiotherapy. We also evaluated the pattern of vascularity and found it to be divided into 3 categories; a hilar pattern, a peripheral pattern and a no-signal pattern. Both previous report and our previous study supported the theory that either the displaced hilar flow or the absence of local perfusion indicates a malignant nature of lymph nodes and therefore, we evaluated any abnormalities in a hilar pattern. Results Irradiation of the neck (22.5Gy or 30Gy) caused an increase of blood inflow into the lymph nodes and better visualization of the peripheral vessels. The incidence of a no-signal pattern decreased from 27% before irradiation to 7% after irradiation. Preoperative irradiation improved the detection of an abnormal hilar flow in the metastatic nodes and the incidence increased from 45% to 74%. If an abnormal blood flow (a no-signal pattern, a peripheral pattern and an abnormal hilar pattern) was a criterion for metastasis, the discriminative power was increased with sensitivity from 72% to 86%, specificity from 64% to 89%. Conclusion After irradiation, the reduction of percentage of reactive nodes of no-signal pattern and the better detection of an abnormal hilar flow in metastatic nodes improved the discriminative power. (author abst.)