PREOPERATIVE CHEMORADIOTHERAPY USING SUPERSELECTIVE INTRAARTERIAL INFUSION VIA SUPERFICIAL TEMPORAL ARTERY FOR STAGE III, IV ORAL CANCER
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Accession number;04A0146769
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| Title;PREOPERATIVE CHEMORADIOTHERAPY USING SUPERSELECTIVE INTRAARTERIAL INFUSION VIA SUPERFICIAL TEMPORAL ARTERY FOR STAGE III, IV ORAL CANCER |
| Author;
TONAI IWAI
(Nagoya Univ., Graduate School of Medicine, JPN)
HAYASHI YASUSHI
(Nagoyadai2nissekibyoin Shikakokugeka)
SHIGETOMI TOSHIO
(Nagoya Univ., Graduate School of Medicine, JPN)
MITSUDO KENJI
(Nagoya Univ., Graduate School of Medicine, JPN)
FUKUI TAKAFUMI
(Nagoya Univ., Graduate School of Medicine, JPN)
FUKUHARA HIROKAZU
(Nagoya Univ., Graduate School of Medicine, JPN)
YAMAMOTO NORIYUKI
(Nagoya Univ., Graduate School of Medicine, JPN)
ISHIGAKI TAKEO
(Nagoya Univ., Graduate School of Medicine, JPN)
FUWA NOBUKAZU
(Aichi Cancer Center, JPN)
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Journal Title;Head and Neck Cancer
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Journal Code:Y0503A
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ISSN:0911-4335
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VOL.28;NO.1;PAGE.253-258(2002)
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| Figure&Table&Reference;FIG.5, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Thirty-eight patients with stage III, IV oral cancer were treated by preoperative chemoradiotherapy using superselective intraarterial infusion via the superficial temporal artery. Radiotherapy (total dose: 40Gy) and chemotherapy using CBDCA (total dose: 460mg/m2) were performed daily, followed by surgery. Catheter-insertion of 34 patients was done successfully. Four catheter insertions were not done successfully because of the anomaly of the artery such as common trunk of the lingual artery and the facial artery. The clinical effects were CR in 9 patients (26.5%) and PR in 25 (73.5%), and histopathological effects after surgery were grade III, IV in 10 (29.4%), grade IIb in 23 (67.6%), and grade IIa in 2 (5.8%). The 5-year cumulative survival rate was 67.8%. This superselective intra arterial infusion method could be the technique of choice for the treatment of oral cancer. (author abst.) |
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