The new efficacy of niacinamide in the skin and the application to the skin care products of cosmetics.

Accession number;04A0147401
Title;The new efficacy of niacinamide in the skin and the application to the skin care products of cosmetics.
Author; TANNO OSAMU (Kanebo Ltd., JPN)
Journal Title;Fragr J
Journal Code:G0987B
ISSN:0288-9803
VOL.32;NO.2;PAGE.35-39(2004)
Figure&Table&Reference;FIG.5, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;Niacin and niacinamide play an important role as coenzymes, NAD+ and NADP+ in the skin. Recently, some studies of new efficacy of niacinamide were reported that it may work through without NAD+ and NADP+. We had reported the new efficacy of niacinamide that increased the synthesis of the stratum cornerum lipids. The topical application of niacinamide improved the water contents and the TEWL of the winter xerosis. In this paper, I present other possibility of niacinamide in the skin. Niacinamide suppress the scratching of NC mice and decrease the stinging score for sensitive skin. Niacinamide also prevents and improves the acne. Finally, I discuss about the new efficacy of niacinamide for skincare products. (author abst.)