Radiofrequency Ablation of liver tumors-preliminary report-

Accession number;04A0165430
Title;Radiofrequency Ablation of liver tumors-preliminary report-
Author; TAMAKI KATSUYOSHI (Univ. of Tokushima, Sch. of Med.) SHIBATA HIROSHI (Taoka Byoin) URATA MARI (Univ. of Tokushima, Sch. of Med.) ITAGAKI TATSUZO (Univ. of Tokushima, Sch. of Med.) OSHIO ATSUO (Univ. of Tokushima, Sch. of Med.) IMOTO YOSHITAKA (Univ. of Tokushima, Sch. of Med.) OKAMOTO KOICHI (Univ. of Tokushima, Sch. of Med.) SATO YASUNORI (Univ. of Tokushima, Sch. of Med.) AOKI RIKA (Univ. of Tokushima, Sch. of Med.)
Journal Title;Shikoku Acta Medica
Journal Code:G0586A
ISSN:0037-3699
VOL.59;NO.6;PAGE.287-291(2003)
Figure&Table&Reference;FIG.2, TBL.2, REF.6
Pub. Country;Japan
Language;Japanese
Abstract;Radiofrequency ablation (RFA) has recently been used to treat liver tumors. RFA is a safe and effective treatment of liver tumors and requires fewer treatment sessions. Between June 2000 and April 2003, hepatocellular carcinoma (77 patients with 106 lesions) and metastatic liver tumors (21 patients with 30 lesions) and cholangiocellular carcinoma (1 patient with 1 lesion) were treated with RFA. The liver tumors were treated percutaneously or during surgery under ultrasound guidance using a LeVeen needle (55 lesions) and cool tip RF needle (82 lesions). To evaluate the response, contrast-enhanced CT scans or MRI were obtained. Most patients experienced moderate pain during RFA procedure, especially when the tumor was superficially located. Complete necrosis was achieved in all HCCs with RFA. This result was obtained with an average of 1.12 sessions per HCC. With a median follow-up of 15 months, HCCs have recurred in 6 of 90 treated lesions (6.7%), and metastatic liver tumors have recurred in 2 of 17 treated lesions (11.8%). We are initiating a combining RFA of hepatic malignancies with regional or systemic chemotherapy will reduce hepatic and extrahepatic recurrence rates and enhance long-term survival rates. We believe that RFA will be effective treatment to achieve in patients with unresectable meastatic liver tumors. (author abst.)