Management of Osteoporosis during Steroid Pulse Therapy for Ophthalmologic Diseases
|
Accession number;04A0178227
|
| Title;Management of Osteoporosis during Steroid Pulse Therapy for Ophthalmologic Diseases |
| Author;
NUMAGA JIRO
(Tokyo Metropolitan Geriatric Medical Center, JPN)
|
Journal Title;Journal of the Eye
|
Journal Code:Y0754A
|
ISSN:0910-1810
|
|
VOL.21;NO.2;PAGE.279-281(2004)
|
| Figure&Table&Reference;TBL.1, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Since the beneficial effects of adrenocortical steroid (hereinafter referred to as steroid) pulse therapy on Vogt-Koyanagi-Harada disease were reported, this therapeutic technique has been used more frequently in clinical practice. The steroid plays an indispensable role in the treatment of various pathological conditions, such as ophthalmologic disease, collagen disease, hematological disorder and neuroimmunological disorder. However, the development of adverse effects, including osteoporosis, has been pointed out. Bone fracture occurs as a complication of steroid-induced osteoporosis, which seriously diminishes the patient's quality of life and adversely affects prognosis. The present authors report on giving individuals undergoing steroid therapy a vitamin K2 preparation to prevent steroid-induced osteoporosis, and discuss the significance of this combined treatment from the aspect of preventive medicine. Guidelines for preventing and treating steroid-induced osteoporosis have already been established abroad. Therefore, ophthalmologists are expected to fully understand the pathology of steroid-induced osteoporosis and introduce effective preventive measures in cases where the steroid is used. (author abst.) |
|
|
|
Related Articles;
|
|
