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Accession number;04A0211073
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| Title;Acrylamide Does Not Cause Apparent Changes in Genetic Expression of Creatine Kinase in Rat Cerebellum. |
| Author;
WISPRIYONO B
(Univ. Occupational And Environmental Health, Kitakyushu, Jpn)
MATSUOKA M
(Univ. Occupational And Environmental Health, Kitakyushu, Jpn)
IGISU H
(Univ. Occupational And Environmental Health, Kitakyushu, Jpn)
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Journal Title;J UOEH Occup Environ Health
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Journal Code:Z0840A
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ISSN:0387-821X
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VOL.26;NO.1;PAGE.51-57(2004)
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| Figure&Table&Reference;FIG.2, REF.11 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Acrylamide inhibits creatine kinase (CK) activities in the brain of rats or mice. However, its effects on genetic expression of CK have not yet been studied. CK mRNA and protein level were examined by RT-PCR and Western blotting, respectively. Neither cytosolic CK (B subunit) and mitochondrial CK (ubiquitous form) mRNA nor B subunit protein was clearly changed in the cerebellum from rats intoxicated with acrylamide (50 mg/kg/day ip for 8 days) and showing clinical neurotoxic signs. (author abst.) |
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