Hyperviscosity syndrome in a case of polyclonal hypergammaglobulinemia
|
Accession number;04A0241641
|
| Title;Hyperviscosity syndrome in a case of polyclonal hypergammaglobulinemia |
| Author;
OSHIMA HARUKA
(Jichi Medical School, Dep. Medicine, JPN)
MAKINO SHINJI
(Jichi Medical School, Dep. Medicine, JPN)
KONDO CHIKA
(Jichi Medical School, Dep. Medicine, JPN)
KANAGAMI SADAO
(Jichi Medical School, Dep. Medicine, JPN)
TSURU TADAHIKO
(Jichi Medical School, Dep. Medicine, JPN)
|
Journal Title;Japanese Journal of Clinical Ophthalmology
|
Journal Code:Z0515B
|
ISSN:0370-5579
|
|
VOL.58;NO.3;PAGE.309-313(2004)
|
| Figure&Table&Reference;FIG.5, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A 72-year-old woman was referred to us for retinal hemorrhage. She had noticed blurring of vision 4 months before. Her corrected visual acuity was 0.5 right and 0.3 left. The retinal vessels showed marked beading and tortuosity. There were, additionally, retinal and vitreous hemorrhage, capillary microaneurysms, and macular edema. The peripheral retina had become avascular. These findings were suggestive of hyperviscosity syndrome. Laboratory studies showed anemia and rouleau formation of erythrocytes. Serum proteins showed increased levels of 10.8 g/dl for total protein, 4,205 mg/dl for IgG, 463 mg/dl for IgM, and 719 mg/dl for IgA. Immunoelectrophoresis showed polyclonal hypergammaglobulinemia. The serum viscosity was 12.2cP. We diagnosed her as retinopathy seconary to hyperviscosity syndrome. She was treated by systemic anticoagulants and photocoagulation to the peripheral retina. After 8 months, the serum viscosity decreased to 9.16cP. Funduscopy showed improved venous beading, tortuosity, and macular edema. The visual acuity improved to 0.6 right and 0.5 left. This case illustrates that hyperviscosity retinopathy may be reversible following successful anticoagulant therapy. (author abst.) |
|
|
|
Related Articles;
|
|
