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Accession number;04A0258627
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| Title;Design and application of de novo peptides capable to bind metal ions. |
| Author;
MIZUNO TOSHIHISA
(Nagoya Inst. of Tech., Grad. Sch.)
KOIKE MIHOKO
(Nagoya Inst. of Tech., Grad. Sch.)
WADA KIYOKO
(Nagoya Inst. of Tech., Grad. Sch.)
TAJIMA KUNIHIKO
(Kyoto Inst. Technol., JPN)
HIROAKI HIDEKAZU
(Yokohamashisori)
OKU JUN'ICHI
(Nagoya Inst. of Tech., Grad. Sch.)
TANAKA TOSHIKI
(Nagoya Inst. of Tech., Grad. Sch.)
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Journal Title;Abstracts. Symposium on Biofunctional Chemistry
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Journal Code:L0836A
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ISSN:
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VOL.18th;NO.;PAGE.90-91(2003)
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| Figure&Table&Reference;FIG.4 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;In nature there exist many redox-proteins which containing different metal ions into their skeletones, like Superoxide Disumutase (SOD), Nitorogenase Fe-Mo protein and so on. Here we designed coiled-coil peptide aggregates capable to bind different metal ions at hydrophobic core. Mutating some of amino acids at hydrophobic core, selective binding for Ni(II) and Cu(II) was realized. (author abst.) |
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