Factors Affecting the Olfactory Prognosis in Endoscopic Endonasal Sinus Surgery

Accession number;04A0278619
Title;Factors Affecting the Olfactory Prognosis in Endoscopic Endonasal Sinus Surgery
Author; SUZUKI EMIKO (Showa Univ., JPN) SHIBUYA ENATSU (Showa Univ., JPN) ASAHINA NORIHIKO (Showa Univ., JPN) SUZAKI HARUMI (Showa Univ., JPN)
Journal Title;Practica Otologica (Kyoto)
Journal Code:G0710A
ISSN:0032-6313
VOL.97;NO.4;PAGE.299-306(2004)
Figure&Table&Reference;FIG.6, REF.25
Pub. Country;Japan
Language;Japanese
Abstract;Endoscopic endonasal sinus surgery was conducted in 92 patients who had chronic sinusitis with moderate or severe olfactory dysfunctions. Improvements of olfaction in these patients were investigated by employing T & T olfactometry, a standard olfactory test procedure used in Japan, before and after the surgery. In measurements made 6 to 12 months after surgery, 67 had improved olfaction, while 25 showed no improvement. Statistical analysis was performed to identify the factors that may affect the olfaction outcome after endoscopic endonasal sinus surgery. Factors investigated included age at the time of surgery, complication with allergic rhinitis or bronchial asthma, nasal symptoms (nasal congestion, rhinorrhea, and postnasal drip), results of pre-surgical T & T olfactometry, endoscopic findings of the olfactory cleft, intravenous olfaction test (Alinamine injection test), and severity of chronic sinusitis observed by CT. The following were detected significantly more frequently in the group with no improvement in post-operative olfaction: duration of olfactory dysfunction of 7 or more years, history of surgery of the nose and paranasal sinuses; lack of response to the pre-operative intravenous olfaction test; and the formation of polyps at the olfactory cleft, which was detected during the pre-operative endoscopic examination. We concluded that these factors most markedly affect improvement in olfaction after endoscopic endonasal sinus surgery for chronic sinusitis. (author abst.)