Precorneal Movement of Ophthalmic Solution Dissolved in Reversible Thermosetting Gel and Its Effect on Secondary Ophthalmic Solution.
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Accession number;04A0276151
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| Title;Precorneal Movement of Ophthalmic Solution Dissolved in Reversible Thermosetting Gel and Its Effect on Secondary Ophthalmic Solution. |
| Author;
IKEDA ERI
(Dokkyo Univ. Sch. of Med.)
TERADA OSAMU
(Dokkyo Univ. Sch. of Med.)
KISHIMOTO YOKO
(Dokkyo Univ. Sch. of Med.)
CHIBA KEIZO
(Dokkyo Univ. Sch. of Med.)
OBARA YOSHITAKA
(Dokkyo Univ. Sch. of Med.)
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Journal Title;Journal of the Eye
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Journal Code:Y0754A
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ISSN:0910-1810
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VOL.21;NO.3;PAGE.401-404(2004)
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| Figure&Table&Reference;FIG.6, REF.6 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;In 40 eyes of 20 control subjects (age: 29.2.+-.11.3 yrs; mean.+-.SD), we observed precorneal movement of ophthalmic solution in reversible thermosetting gel and investigated the effect on secondary ophthalmic solution. 1) After one drop of gel, we observed precorneal movement via dry eye machine. Gel was observed for 20 minutes, but disappeared after 20 minutes. 2) We then substituted fluorescein for secondary ophthalmic solution. After instillation of 15 .MU.l of gel, we instilled 15 .MU.l of fluorescein immediately; then at 5, 10, 15, 20, 30 and 45 minutes we investigated precorneal fluorescein after fluorescein eyedrops using a fluorometer (Kowa Co., Ltd., Japan). We controlled the single fluorescein eyedrop. Fluorescein showed signifant decrease at 10 minutes and significant increase at 15 minutes after instillation. However, there was no significant difference since 20 minutes. Gel can remain on the ocular surface at 20 minutes after instillation, and may have a direct influence on secondary eyedrops. (author abst.) |
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