UV-induced immune suppression and anti-oxidative treatment.
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Accession number;04A0360699
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| Title;UV-induced immune suppression and anti-oxidative treatment. |
| Author;
IWAI ICHIRO
(Shiseido Co., Ltd., JPN)
KUWAHARA TOMOHIRO
(Shiseido Co., Ltd., JPN)
HATAO MASATO
(Shiseido Co., Ltd., JPN)
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Journal Title;Fragr J
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Journal Code:G0987B
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ISSN:0288-9803
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VOL.32;NO.4;PAGE.41-48(2004)
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| Figure&Table&Reference;FIG.12, REF.50 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;It is well known that ultraviolet (UV) radiation suppresses immune function and was considered as a major cause of a certain type of skin cancers. In this study, we investigated the effects of UV and oxidative stress on immune function using several in vitro cell culture models. As a result, it is demonstrated that UV damaged the immune function via an oxidative pathway, and the immune suppression was mitigated by anti-oxidative treatment. These results support the hypothesis that UV-induced immune suppression is at least partially mediated by reactive oxygen species. (author abst.) |
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