The Effect of Substituting Latanoprost 0.005% for Unoprostone 0.12%
|
Accession number;04A0381226
|
| Title;The Effect of Substituting Latanoprost 0.005% for Unoprostone 0.12% |
| Author;
OTORI YASUMASA
(Graduate School of Medicine, Osaka Univ., JPN)
TOKUGAWA HIDEKI
(Osaka Railw. Hosp.)
MORIMURA HIROYUKI
(Mutualaid Assoc. Public. School Teach., Kinki Central Hospital, JPN)
OKADA MASAKI
(Graduate School of Medicine, Osaka Univ., JPN)
GOTO HIROYA
(Graduate School of Medicine, Osaka Univ., JPN)
MIKI ATSUYA
(Graduate School of Medicine, Osaka Univ., JPN)
TANO YASUO
(Graduate School of Medicine, Osaka Univ., JPN)
|
Journal Title;Journal of Japanese Ophthalmological Society
|
Journal Code:Z0666A
|
ISSN:0029-0203
|
|
VOL.108;NO.4;PAGE.207-212(2004)
|
| Figure&Table&Reference;FIG.3, TBL.1, REF.20 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Purpose: To evaluate the effect of substituting latanoprost (LAT) 0.005% for unoprostone (UNO) 0.12% after a trial of unilateral treatment. Methods: We treated 30 patients with primary open-angle glaucoma (n=8), ocular hypertension (n=l), or normal-tension glaucoma (n=21) with UNO for 4 weeks in one eye and then substituted LAT for UNO. Four weeks later we measured the intraocular pressure (IOP) in the ipsilateral eye. Results: The mean baseline IOP level was 18.6.+-. 3.8(mean.+-.standard deviation)mmHg. The mean IOP levels (reduction rates) after UNO and LAT therapy were 16.7.+-.3.1 mmHg(16.6 %) and 14.1.+-.3.2mmHg(28.9%), respectively(p<0.001). All patients who responded to UNO also responded to LAT ; however, 55% of those who did not respond to UNO responded to LAT. Conclusions: If LAT is substituted for UNO, it can be predicted that 63.3 % of the patients will respond. (author abst.) |
|
|
|
Related Articles;
|
|
|
