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Accession number;04A0122670
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| Title;Physiology and Pathophysiology of Dermal Dendritic Cells |
| Author;
AIBA SETSUYA
(Tohoku Univ., Graduate School of Medicine, JPN)
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Journal Title;Rinsho Derma (Tokyo)
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Journal Code:Z0122B
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ISSN:0018-1404
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VOL.46;NO.1;PAGE.55-63(2004)
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| Figure&Table&Reference;FIG.7, REF.47 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;It was introduced that the dermis dendritic cells formed the subpopulation of the dendritic cells unlike Langerhans cells. The differentiation of dendritic cells from the hemopoietic precursor cells was explained. The type of the dendritic cells, which existed in the skin, was described. It was shown that the fibroblast of the skin induced the differentiation of the dendritic cells. Differentiated dendritic cells have manifested factor XIIIa without having Birbeck granule. The antigen presentation function was mentioned as a function of the dermis dendritic cells. The role of DC-SIGN in which the dendritic cells appeared was explained in detail. As functions except for this, the actions in which factor XIIIa and collagen XVI were concerned were mentioned. The relation of dermis dendritic cells and histamine receptor expression was examined. The disease in which factor XIIIa positive cells such as inflammatory dermatosis and neoplastic dermatosis (dermatofibroma) increased was described. The disease in which it decreased was also described. |
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