An In Vitro Chemosensitivity Test against Canine Mammary gland Tumors Using Collagen Gel Droplet Embedded Cultures
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Accession number;04A0543126
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| Title;An In Vitro Chemosensitivity Test against Canine Mammary gland Tumors Using Collagen Gel Droplet Embedded Cultures |
| Author;
KITAGAWA HITOSHI
(Gifu Univ., JPN)
OBA YASUNORI
(Gifu Univ., JPN)
WATANABE KAZUHIRO
(Gifu Univ., JPN)
FUKATA TSUNEO
(Gifu Univ., JPN)
TAKANO TOSHIKAZU
(Nitta Gelatine Inc., JPN)
KOBAYASHI HISAYUKI
(Nitta Gelatine Inc., JPN)
KITO KATSUYA
(Gifu Univ., JPN)
YAMAZOE KAZUAKI
(Gifu Univ., JPN)
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.57;NO.7;PAGE.441-445(2004)
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| Figure&Table&Reference;FIG.4, TBL.1, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Our basic study on the usefulness of the collagen gel droplet embedded culture drug-sensitivity test (CD-DST) showed that canine mammarygland tumor cells can be cultured well in collagen gel droplets. With this method, we employed five kinds of anticancer drugs-adriamycm, 4OH-cyclophosphamide, vincristine, 5-fluorouracil, and predonisolone-against tumor cells. An image-analysis system was used to analyze their in vitro anticancer activities. We found that anti-cancer drug efficacy against canine mammary gland tumors differed from dog to dog. The CD-DST method can be applied to canine tumors and may be an index for so-called custum-made therapy. (author abst.) |
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