Effect of Ocular Hypotensive Medications in Preventing the Progression of Visual Field Damage in Patients with Normal-tension Glaucoma

Accession number;04A0557368
Title;Effect of Ocular Hypotensive Medications in Preventing the Progression of Visual Field Damage in Patients with Normal-tension Glaucoma
Author; NAKAGAMI TAKAKO (School of Medicine, Nihon Univ., JPN) YAMAZAKI YOSHIO (School of Medicine, Nihon Univ., JPN) HAYAMIZU FUKUKO (School of Medicine, Nihon Univ., JPN) TANAKA CHIZURU (School of Medicine, Nihon Univ., JPN)
Journal Title;Journal of Japanese Ophthalmological Society
Journal Code:Z0666A
ISSN:0029-0203
VOL.108;NO.7;PAGE.408-414(2004)
Figure&Table&Reference;FIG.2, TBL.6, REF.26
Pub. Country;Japan
Language;Japanese
Abstract;Purpose: We investigated the effect of ocular hypotensive medications and the risk factors for progression of visual field damage in patients with normal-tension glaucoma (NTG). Subjects and Methods: Sixty-four NTG patients (64 eyes) followed at least 4 years with ocular hypotensive medications were studied regarding the probability of visual field stability using the Kaplan-Meier life-table analysis and multiple regression analysis with the Cox proportional hazards model. Results: Probability of visual field stability was 56% at the 76-month follow-up. Mean intraocular pressure during the follow-up period and generalized cup enlargement type classified according to the optic disc shape were found to have significant influence on the progression of visual field damage. Conclusion: These findings suggest that ocular hypotensive medications are effective in stabilizing the visual field. We need to pay attention to the optic disc shape in patients with NTG. (author abst.)