Increase of Activated TGF-.BETA.1 in the Blood of canine Lymphocytic-plasmacytic Gonarthritis
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Accession number;04A0609647
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| Title;Increase of Activated TGF-.BETA.1 in the Blood of canine Lymphocytic-plasmacytic Gonarthritis |
| Author;
KUWABARA MASATO
(Nihon Univ., Coll. Bioresource Sci., JPN)
NARIAI YOKO
(Nihon Univ., Coll. Bioresource Sci., JPN)
YAMAGUCHI YU
(Nihon Univ., Coll. Bioresource Sci., JPN)
NAGAOKA KATSUYOSHI
(Nihon Univ., Coll. Bioresource Sci., JPN)
OBA SHIGEO
(Nihon Univ., Coll. Bioresource Sci., JPN)
KAMATA HIROSHI
(Nihon Univ., Coll. Bioresource Sci., JPN)
YUKAWA MASAYOSHI
(Nihon Univ., Coll. Bioresource Sci., JPN)
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Journal Title;Journal of the Japan Veterinary Medical Association
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Journal Code:Y0220A
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ISSN:0446-6454
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VOL.57;NO.8;PAGE.521-524(2004)
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| Figure&Table&Reference;TBL.3, REF.24 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Immunological examination of two dogs (flat-coated retrievers) diagnosed as lymphocytic-plasmacytic gonarthritis revealed a T-cell subset imbalance in the knee joints and increased activity of transforming-growth factor-.BETA.1 (TGF-.BETA.1) as a Th3 cytokine. This finding suggests that immune abnormality mediated by TGF-.BETA.1 may play a part in the development of this disease. (author abst.) |
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