|
Accession number;04A0685277
|
| Title;Antihypertensive Therapy of Morning Blood Pressure-ATOM Study- |
| Author;
TAMAKI SHINJI
(Koritsukogabyoin Naika)
ONISHI MASATO
(Shigaidai Kokyujunkankinaika)
MORIMOTO SATOSHI
(Omi-Hachiman Munic. Hospital, JPN)
HORIE MINORU
(Shigaidai Kokyujunkankinaika)
|
Journal Title;Japanese Pharmacology & Therapeutics
|
Journal Code:Z0947A
|
ISSN:0386-3603
|
|
VOL.32;NO.8;PAGE.481-486(2004)
|
| Figure&Table&Reference;FIG.6, TBL.2, REF.14 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Background: Several prospective studies have indicated that early morning hypertension and morning blood pressure (BP) surge are important risk factors of stroke or cardiovascular events. We investigated differences between early morning and clinic BP as well as morning BP surge in patients being treated for essential hypertension. Design: We recorded systolic BP at three different times 1) before going to bed and, 2) in the early morning period before visiting the clinic by self-measurement at home, and 3) while at the clinic. Results: Although 40.4% of all patients demonstrated normal systolic BP while at the clinic, 50.3% of those demonstrated early morning hypertension. Only 19.0% of the patients demonstrated normal systolic BP both at the clinic and in the early morning. The mean morning BP surge was 9.16 .+-. 16.9 mmHg. Those patients who had taken valsartan resulted a particularly large surge, and a significant difference was observed between candesartan. Conclusion: These findings suggest that a strategy for controlling BP must be considered not only clinic BP but also morning home BP, and that the duration of BP lowering effects varies between anti-hypertensive agents. (author abst.) |
|
|
|
Related Articles;
|
