Science Links Japan | Relationships Between Intravascular Ultrasonographic Findings and Coronary Risk Factors in Patients With Normal Coronary Angiography

Relationships Between Intravascular Ultrasonographic Findings and Coronary Risk Factors in Patients With Normal Coronary Angiography

Accession number;05A0067668

Title;Relationships Between Intravascular Ultrasonographic Findings and Coronary Risk Factors in Patients With Normal Coronary Angiography

Author; NOIKE HIROFUMI (Toho Univ. School of Medicine., Sakura Hospital, JPN) HITSUMOTO TAKASHI (Toho Univ. School of Medicine., Sakura Hospital, JPN) SAKURAI TAKASHI (Toho Univ. School of Medicine., Sakura Hospital, JPN) SUGIYAMA YUKO (Toho Univ. School of Medicine., Sakura Hospital, JPN) SATO SHIN (Toho Univ. School of Medicine., Sakura Hospital, JPN) IIZUKA TAKUO (Toho Univ. School of Medicine., Sakura Hospital, JPN) TAKAHASHI MAO (Toho Univ. School of Medicine., Sakura Hospital, JPN) SHIMIZU KAZUHIRO (Toho Univ. School of Medicine., Sakura Hospital, JPN) NAKAMURA KEIJIRO (Toho Univ. School of Medicine., Sakura Hospital, JPN)

Journal Title;J Cardiol

Journal Code:Y0264A

ISSN:0914-5087

VOL.45;NO.1;PAGE.1-10(2005)

Figure&Table&Reference;FIG.7, TBL.4, REF.18

Pub. Country;Japan

Language;Japanese

Abstract;Objectives. Indicators of ischemic heart disease were studied for the practice of preventive medicine. Methods. Intravascular ultrasonography was performed in 97 patients with no abnormalities by left anterior descending artery angiography. Coronary risk factors were evaluated based on the relationship between plaque formation and lipoprotein levels. Results. Plaque was observed in 81% of patients. The relationship between mean plaque area (%) and the low-density lipoprotein/high-density lipoprotein (LDL/HDL) ratio was examined. Mean plaque area (%) was significantly higher at LDL/HDL.LEQ.2.5 than at LDL/HDL>2.5. The border of significant change level of mean plaque area (%) was LDL/HDL=2.5. There was a good correlation between mean plaque area (%) and LDL/HDL (r=0.65, p<0.01). Mean plaque area (%) at LDL/HDL 2.5 was calculated at 15%. Patients with coronary risk factors had LDL/HDL lower than 2.5 at mean plaque area of 15%. Conclusions. Maintaining LDL/HDL at 2.5 is very important for preventive medicine. However, LDL/HDL should be managed at under 2.5 in patients with coronary risk factors. (author abst.)

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