New Sphingolipids and a Sterol from a Lobophytum Species of the Indian Ocean
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Accession number;05A0106834
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| Title;New Sphingolipids and a Sterol from a Lobophytum Species of the Indian Ocean |
| Author;
MURALIDHAR P
(Andhra Univ., Visakhapatnam, Ind)
KUMAR M M
(Andhra Univ., Visakhapatnam, Ind)
KRISHNA N
(Andhra Univ., Visakhapatnam, Ind)
RAO C B
(Andhra Univ., Visakhapatnam, Ind)
RAO D V
(Andhra Univ., Visakhapatnam, Ind)
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Journal Title;Chem Pharm Bull
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Journal Code:G0504A
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ISSN:0009-2363
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VOL.53;NO.2;PAGE.168-171(2005)
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| Figure&Table&Reference;TBL.1, REF.42 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Chemical investigation of a soft coral species of the genus Lobophytum has resulted in the isolation of three new sphingolipids-(2S,3S,4R)-2-nonadecanoylamino-octadecane-1,3,4-triol (1), (2S,3R,4E,8E)-[(2'R)-2'-hydroxyheptadecanoylamino]-4,8-octadecadiene-1,3-diol (2), 1-O-(.BETA.-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2'R)-2'-hydroxynonadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol (3) and a sterol-(24S)-ergost-5-en-3.BETA.,7.BETA.-diol (4) along with the known sphingolipid-(2S,3R,4E,8E)-2-hexadecanoylamino-4,8-octadecadien-1,3-diol (5) which showed cytotoxicity against human peripheral blood mononuclear cells (PBMC). (author abst.) |
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