Immune memory cells in immune mechanism.
|
Accession number;05A0136079
|
| Title;Immune memory cells in immune mechanism. |
| Author;
TAKAGI ATSUSHI
(Abottojapan)
TAMAI HAJIME
(Eikobyoin)
|
Journal Title;Modern Medical Laboratory
|
Journal Code:Z0084B
|
ISSN:0301-2611
|
|
VOL.33;NO.1;PAGE.42-43(2005)
|
| Figure&Table&Reference;FIG.4, REF.1 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Recent knowledge on immune memory cell (I) is outlined. When a pathogen invades for the first time, phagocytes gormandize to present the antigen to naive T-cell. Naive T-cell is differentiated into TH1 and TH2, and TH1 stimulates immature cytotoxic T-cell and TH2 stimulates immature B-cell, each to differentiate into effector cell and (I), respectively. Though effector cells almost die out after the expulsion of the pathogen, (I) suspends cell division to be at a rest, preparing for reinfection. The immune reaction caused by (I) due to reinfection is called a secondary reaction, and (I) shows a quicker, stronger and more specific immune response to the re-encountered antigen than the immune response at the first time. Since the memory B-cell and the antibody scramble for the remaining little antigen in the secondary response, and since the B-cell with the higher affinity wins the competition, the affinity of the produced antibody rises in the secondary immune response. |
|
|
|
Related Articles;
|
|
