Abnormal values in oxygen test Amylase anomaly.

Accession number;05A0136088
Title;Abnormal values in oxygen test Amylase anomaly.
Author; MORIYAMA TAKANORI (Hokudai I Hokengakka Kensagijutsukagakusenko)
Journal Title;Modern Medical Laboratory
Journal Code:Z0084B
ISSN:0301-2611
VOL.33;NO.1;PAGE.74-75(2005)
Figure&Table&Reference;FIG.2, REF.10
Pub. Country;Japan
Language;Japanese
Abstract;As seral amylase anomaly reported by amylase electrophoresis, genetic variation (pancreatic-derived and saliva-derived variants), macroamylase (immunoglobulin complex/complex with substrate), tumor-productive amylase (sialyl-S amylase) are taken up, and the appearance mechanism and clinical significance are outlined. The anomaly most often detected and with most important significance in clinical diagnosis is macroamylase (amylase-immunoglobulin complex). Since this immunoglobulin complex show persistent hyperamylasemia of unkown origin in most cases, it is important to diagnose in the labolatory for avoiding excessive examination and misdiagnosis. The diagnosis can be facilitated by non-fractional broad band detection in electrophoresis or detection of macromolecular amylase fraction in gel filtration.