Assessment of Regional Myocardial Systolic Function in Hypertensive Left Ventricular Hypertrophy Using Harmonic Myocardial Strain Imaging

Accession number;05A0202004
Title;Assessment of Regional Myocardial Systolic Function in Hypertensive Left Ventricular Hypertrophy Using Harmonic Myocardial Strain Imaging
Author; MANAKA MAKI (Tokyo Medical Univ., JPN) TANAKA NOBUHIRO (Tokyo Medical Univ., JPN) TAKEI YASUYOSHI (Tokyo Medical Univ., JPN) KUROHANE SAIKO (Tokyo Medical Univ., JPN) TAKAZAWA KENJI (Tokyo Medical Univ., JPN) YAMASHINA AKIRA (Tokyo Medical Univ., JPN)
Journal Title;J Cardiol
Journal Code:Y0264A
ISSN:0914-5087
VOL.45;NO.2;PAGE.53-60(2005)
Figure&Table&Reference;FIG.9, TBL.1, REF.28
Pub. Country;Japan
Language;Japanese
Abstract;Objectives. Regional myocardial systolic function in hypertensive left ventricular hypertrophy was assessed using the newly developed myocardial strain imaging. Methods. This study included 17 patients with hypertensive left ventricular hypertrophy (LVH group) and 22 normal subjects (N group). The transmural location of the strain peak value (StPP), and the strain peak value (StPV) in the end-systolic phase were measured at the posterior wall by myocardial strain imaging. Left ventricular mass index was simultaneously measured in both groups. Results. StPV was significantly lower in the LVH group than the N group (1.00.+-.0.36 vs 1.38.+-.0.42, p<0.01) and StPP was significantly moved to the epicardium side compared with the N group (31.+-.10% vs 11.+-.5%, p<0.0001). StPV decreased and StPP increased with greater left ventricular mass index (r=-0.61, p<0.0001; r=0.72, p<0.0001, respectively). Conclusions. Myocardial systolic impairment in hypertensive left ventricular hypertrophy may occur from the endocardium side, and the impairment may progress with increased left ventricular hypertrophy. (author abst.)
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