Fatal Fulminant Infection of Clostridium Perfringens
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Accession number;05A0222415
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| Title;Fatal Fulminant Infection of Clostridium Perfringens |
| Author;
SHIMIZU KEIKI
(Saitamasekijujibyoin Kyumeikyukyuse Kyukyuigakka)
KOSHIMA YOHEI
(Saitamasekijujibyoin Kyumeikyukyuse Naika)
KATO HARU
(National Inst. Infectious Diseases, JPN)
ARAKAWA YOSHICHIKA
(National Inst. Infectious Diseases, JPN)
YOKOTE RYO
(Saitamasekijujibyoin Kyumeikyukyuse Kyukyuigakka)
SUGITA MANABU
(Saitamasekijujibyoin Kyumeikyukyuse Kyukyuigakka)
MIYAKE YASUFUMI
(School of Medicine, Showa Univ., JPN)
KIYOTA KAZUYA
(Saitamasekijujibyoin Kyumeikyukyuse Kyukyuigakka)
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Journal Title;Japanese Journal of Intensive Care Medicine
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Journal Code:Z0581B
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ISSN:0389-1194
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VOL.29;NO.1;PAGE.63-70(2005)
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| Figure&Table&Reference;FIG.7, TBL.2, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Deaths caused by fulminant Clostridium perfringens infection have been sporadically reported in recent years. This study describes a case of fulminant C. perfringens infection that occurred with in a short period of time despite intensive care. The patient was a 57-year-old man with diabetes. He was seen by a local physician following the appearance of epigastralgia, fever and diarrhea starting several days ago. Since his condition did not improve on the following day, he was examined at the department of internal medicine of our hospital. He was allowed to return home as no prominent findings were observed. After returning home, hematuria was observed. Therefore, he was reexamined later that evening. The blood chemistry showed prominent hemolysis and abdominal echography and CT revealed a mass-like lesion and gas in the S6 region of the liver. Under a diagnosis of liver abscess, he underwent transcutaneous abscess drainage. Soon after the drainage he fell into deep shock with extreme hemolysis. Regardless of intensive treatment with massive vasopressors and blood transfusion, he died four hours after admission. C, perfringens was identified from the abscess and blood cultures. Production of .ALPHA.-toxin was later confirmed, and the causative organism was determined to be type A C. perfringens by PCR. (author abst.) |
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