Blood Purification

Accession number;05A0313191
Title;Blood Purification
Author; ABE RYUZO (Graduate School of Medicine, Chiba Univ., JPN) HIRASAWA HIROYUKI (Graduate School of Medicine, Chiba Univ., JPN) ODA SHIGETO (Graduate School of Medicine, Chiba Univ., JPN) SHIGA HIDETOSHI (Graduate School of Medicine, Chiba Univ., JPN) MATSUDA KEN'ICHI (Graduate School of Medicine, Chiba Univ., JPN) NAKAMURA MASATAKA (Graduate School of Medicine, Chiba Univ., JPN) WATANABE EIZO (Graduate School of Medicine, Chiba Univ., JPN)
Journal Title;Japanese Journal of Intensive Care Medicine
Journal Code:Z0581B
ISSN:0389-1194
VOL.29;NO.2;PAGE.131-137(2005)
Figure&Table&Reference;FIG.4, REF.22
Pub. Country;Japan
Language;Japanese
Abstract;The artificial liver support (ALS) using blood purification plays a central role in the medical intensive care on fulminant hepatitis (FH) patients. Furthermore, the purpose of those blood purification is not only supporting a failing liver function but also preventing other organs' dysfunction and bridging to liver transplantation. We have established ALS system with slow plasma exchange plus high flow dialysate continuous hemodiafiltration that can overcome adverse effects that might be developed when plasma exchange alone applied. The ALS system also improved consciousness and general condition of FH patients, gaining time for liver regeneration. However, some patients need liver transplantation if their liver functions do not recover for a long time and even on those cases ALS is needed as a bridge to transplantation and bridge to recovery. In the future ALS as a bridge to regeneration will possibly contribute to the expansion of the indication for liver transplantation and improve the survival from FH. (author abst.)