Study on Sedative Levels Using Ramsey Sedation Score and Administration Methods of Propofol
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Accession number;05A0313192
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| Title;Study on Sedative Levels Using Ramsey Sedation Score and Administration Methods of Propofol |
| Author;
KAWASE MASAKI
(Tosei General Hospital, JPN)
SHITAOKOSHI AKIRA
(Tosei General Hospital, JPN)
IWATA ASAKO
(Tosei General Hospital, JPN)
KATO KEIKO
(Tosei General Hospital, JPN)
ICHIHARA TOSHIHIKO
(Tosei General Hospital, JPN)
KO TAKU
(Tosei General Hospital, JPN)
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Journal Title;Japanese Journal of Intensive Care Medicine
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Journal Code:Z0581B
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ISSN:0389-1194
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VOL.29;NO.2;PAGE.139-144(2005)
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| Figure&Table&Reference;FIG.2, TBL.3, REF.17 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The purpose of this study is to clarify the relationships among the sedative levels using propofol, its administration methods and the problems involved. The periods of sedation were investigated in 19 critically ill patients who were undergoing continuous infusion of propofol, tracheal intubation and mechanical ventilation. The sedative periods were compared by the term of Ramsey Sedation Score of 2 (Rss 2) and the term of Ramsey Sedation Score above 3 (Rss 3). The sedative duration of time and the frequency of propofol administration had no significant differences between Rss 2 and Rss 3. But, the infusion rate of propofol were higher in Rss 3 than in Rss 2 (Rss 2: Rss 3; 1.36.+-.0.55:1.71.+-.0.65mg/kg/hr, p<0.05). In Rss 2 the rate of administration of propofol was increased at a higher frequency than in Rss 3 (0.078.+-.0.072: 0.006.+-.0.01/hr, p<0.05), while in Rss 3 it was decreased at a higher frequency than in Rss 2 (0.014.+-.0.04: 0.042.+-.0.091/hr, p<0.05). In Rss 2 body movement, discomfort and arousal were seen significantly more frequent than in Rss 3, while in Rss 3 the deep sedative level shown by hypotension and unconsciousness was observed with statistical significance. These results suggest that Ramsey Sedation Score is a useful indicator of assessing quality of sedation and the problems concerning the sedative levels by propofol. (author abst.) |
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