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Accession number;05A0332875
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| Title;Postoperative Gastric Emptying in Neurologically Impaired Children with Gastroesophagial Reflux |
| Author;
KURODA HIROAKI
(Chibadai Daigakuin'igakukenkyuin Shonigeka)
HIGASHIMOTO YASUYUKI
(Chiba Children's Hospital, JPN)
IWAI JUN
(Chiba Children's Hospital, JPN)
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Journal Title;Japanese Journal of Pediatric Surgery
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Journal Code:Z0323B
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ISSN:0385-6313
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VOL.37;NO.3;PAGE.279-283(2005)
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| Figure&Table&Reference;FIG.4, TBL.1, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Gastroesophageal reflux is a life-threatening problem, particularly in neurologically impaired children. Although surgical intervention significantly improves their quality of life, gastric emptying can still be a problem after a successful operation. This study was designed to evaluate postoperative gastric emptying using radioisotopes. Twenty-three patients underwent Nissen's fundoplication. Sixty-four-minute data was obtained after the injection of formula labeled with 99mTc-DTPA. Time-activity curve was obtained to analyze the half emptying time (T1/2) and the emptying pattern. In seven patients who showed prolonged emptying, the effect of an herbal medicine named Rikkunshito was assessed. T1/2 of the cardiac region was longer than that of the antral region in patients with pyloroplasty. After Rikkunshito trial for 7 patients, whole-stomach T1/2 fell into proper range owing to shortening of cardiac T1/2. All patients showed prolonged emptying, and Rikkunshito improved their gastric dynamics. (author abst.) |
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