Intracoronary Temperature in Patients With Coronary Artery Disease
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Accession number;05A0464559
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| Title;Intracoronary Temperature in Patients With Coronary Artery Disease |
| Author;
SHINDO NAOHISA
(Tokyo Medical Univ., JPN)
TANAKA NOBUHIRO
(Tokyo Medical Univ., JPN)
KOBORI YUICHI
(Tokyo Medical Univ., JPN)
KOBAYASHI HIDEYUKI
(Tokyo Medical Univ., JPN)
TERAMOTO TOMOHIKO
(Tokyo Medical Univ., JPN)
TAKAZAWA KENJI
(Tokyo Medical Univ., JPN)
YAMASHINA AKIRA
(Tokyo Medical Univ., JPN)
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Journal Title;J Cardiol
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Journal Code:Y0264A
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ISSN:0914-5087
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VOL.45;NO.5;PAGE.185-191(2005)
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| Figure&Table&Reference;FIG.6, TBL.2, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Objectives. Measurements of changes in plaque temperature may predict plaque rupture. The present study investigated variations in temperature within the atherosclerotic coronary artery using a pressure guide wire with thermal sensor (dual sensor guide wire). Methods and Results. Seventy-seven patients (78 lesions), who had no significant lesion at the orifice of the culprit coronary artery, were studied. The patients had acute myocardial infarction (22 patients), unstable angina pectoris (20 patients), and stable angina pectoris (35 patients). The thermal sensor was calibrated at the orifice of the coronary artery, and then inserted into the culprit coronary artery. .DELTA.T was defined as the difference between the intracoronary temperature at the position of the pressure gradient and at the orifice. .DELTA.T was higher in patients with acute myocardial infarction and unstable angina pectoris than in patients with stable angina pectoris (0.09.+-.0.07 and 0.07.+-.0.07 vs 0.03.+-.0.04.DEG.C., p<0.001, p=0.02, respectively). There was no significant difference in .DELTA.T between patients with acute myocardial infarction and unstable angina pectoris (p=0.48). Patients with acute myocardial infarction and unstable angina pectoris showed a significant relationship between .DELTA.T and C-reactive protein (r=0.59, p=0.0004). Conclusions. The variations in intracoronary temperature of the culprit coronary arteries in patients with acute coronary syndrome were higher than those in patients with stable angina pectoris. These variations may be related to inflammation of vulnerable plaque. (author abst.) |
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