More Acanthamoeba Keratitis Cases in Malaysia
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Accession number;05A0371122
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| Title;More Acanthamoeba Keratitis Cases in Malaysia |
| Author;
GHANI MOHAMED KAMEL ABD.
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
HAMZAH HANIZA
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
NORDIN ANISAH
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
SUBOH YUSOF
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
HANUM FARIDAH
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
MOKTAR NORHAYATI
(Universiti Kebangsaan Malaysia, Kuala Lumpur, Mys)
AHMAD NORAZAH
(Inst. For Medical Res., Kuala Lumpur)
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Journal Title;Int Med J
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Journal Code:L4914A
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ISSN:1341-2051
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VOL.12;NO.1;PAGE.7-9(2005)
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| Figure&Table&Reference;TBL.3, REF.19 |
| Pub. Country;Japan |
| Language;English |
| Abstract;Introduction: Acanthamoeba keratitis is a rare but one of the most severe and potentially sight threatening ocular parasitic infectious diseases. In Malaysia, the first case of Acanthamoeba keratitis was reported in 1995 involving a woman contact lens wearer. Subsequently more cases were seen, though not reported, but the true incidence is not known since it is not a reportable disease. Materials and Methods: Between June 2002 and December 2002 a total of 44 confirmed cases of keratitis with corneal ulcer were diagnosed by ophthalmologists and their corneal scrapings were sent for culture. The participating hospitals were Hospital UKM (HUKM), Kuala Lumpur Hospital (HKL), The Tun Hussein Onn Eye Hospital (HTHO) and a private clinic. Results: Four (9.1 %) of the 44 cases were found to be culture positive for Acanthamoeba. All 4 cases were women aged between 23-47 years and 3 of them wore contact lenses. Except one, three of them were diagnosed late (after more than 1 month of the initial symptoms) indicating that it was one of the conditions whose diagnosis is most commonly missed at initial presentation. Contact lens wear and improper contact lens hygiene seemed to be important risk factors in the development of this condition. Conclusions: It is our impression that Acanthamoeba keratitis is by no means so rare in Malaysia. As it is now seen frequently enough, it should be considered as part of the differential diagnosis of most cases of presumed microbial keratitis especially if the patient is a contact lens wearer. (author abst.) |
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