Response Period of Combined Fluvoxamine and Milnacipran Treatment for Depression

Accession number;05A0371125
Title;Response Period of Combined Fluvoxamine and Milnacipran Treatment for Depression
Author; MORISHITA SHIGERU (Kyoto Jujo Hospital, Kyoto, Jpn) ARITA SEIZABURO (Kansai Medical School, Osaka, Jpn)
Journal Title;Int Med J
Journal Code:L4914A
ISSN:1341-2051
VOL.12;NO.1;PAGE.25-26(2005)
Figure&Table&Reference;FIG.1, TBL.1, REF.5
Pub. Country;Japan
Language;English
Abstract;Objective: In providing drug treatment, it is important to appear the faster onset of response to patients. Antidepressants typically take two to four weeks to provide substantial benefit. The purpose of this clinical practice was to determine the response period of combined fluvoxamine and milnacipran treatment for depression. Design: Open clinical study. Methods: Open clinical study was carried out among twenty-one depression patients. They were receiving 50 mg of fluvoxamine and 50 mg of milnacipran to treat depression. Results: The cumulative percentage of responder receiving fluvoxamine and milnacipran reached over 80% after three weeks. Conclusion: Combined treatment may have a faster onset of response than monotherapy treatment. (author abst.)