Heart Failure and NPPV

Accession number;05A0468414
Title;Heart Failure and NPPV
Author; KOITO HITOSHI (Kansaiidai Otokoyamabyoin Naika)
Journal Title;Japanese Journal of Intensive Care Medicine
Journal Code:Z0581B
ISSN:0389-1194
VOL.29;NO.3;PAGE.189-199(2005)
Figure&Table&Reference;FIG.4, REF.52
Pub. Country;Japan
Language;Japanese
Abstract;The effects of noninvasive positive pressure ventilation (NPPV) on acute cardiogenic pulmonary edema (ACPE) are improvement of oxygenation, respiratory muscular unloading, hemodynamic support and reduction of sympathetic nervous activity. Continuous positive airway pressure (CPAP) and bilevel positive airway pressure (Bilevel-PAP) improved SpO2, SaO2, PaCO2, pH, respiratory rate, heart rate and arterial blood pressure, and reduced intubation rate, but not shortened ventilation period or stay in ICU and hospital. CPAP showed a tendency to reduce mortality and there are qualified recommendations for its use in ACPE. The candidate of NPPV in ACPE is a patient who expected to be improved symptom for a relatively short period. In case NPPV is not successful, the invasive respiratory support including endotrachial intubation should be done without delay. CPAP, Bilevel-PAP and adaptive pressure support servo-ventilation have the possibility to improve cardiac function, quality of life and mortality in patients with chronic congestive heart failure and Cheyne-Stokes respiration. With these therapy, improvement of a sleep quality and a left ventricular ejection fraction, and the reduction of frequency of ventricular ectopic beats, grade of mitral regurgitation and sympathetic nervous activity were reported, only the usefulness of CPAP, however, was confirmed by randomized control trial. (author abst.)